Exposure equivalence between IV (0.8 mg/kg) and oral (1 mg/kg) busulfan in adult patients
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چکیده
منابع مشابه
Population pharmacokinetics of oral high-dose busulfan in adult patients undergoing hematopoietic stem cell transplantation
BACKGROUND AND THE PURPOSE OF THE STUDY Many factors have been reported that contribute to the wide intra- and inter-patient variability of Busulfan (Bu) disposition. The purpose of this study was to develop a population pharmacokinetic model and to determine the covariates affecting the pharmacokinetics (PK) of Bu in Iranian adult patients who received oral high-dose as a conditioning regimen ...
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ژورنال
عنوان ژورنال: European Journal of Clinical Pharmacology
سال: 2009
ISSN: 0031-6970,1432-1041
DOI: 10.1007/s00228-009-0652-5